Quadruply hydrogen bonding modules as highly selective nanoscale adhesive agents.
نویسندگان
چکیده
Covalently linking DNA base analogues DAN, DeUG, or UPy to glass slides led to functional surfaces that could be glued together using a functionalized polystyrene displaying the complementary recognition unit. Nonspecific adhesion was minimized with fluorinated alkane (Teflon-like or Scotchgard-like) surfaces.
منابع مشابه
Azobenzene dye-coupled quadruply hydrogen-bonding modules as colorimetric indicators for supramolecular interactions
The facile coupling of azobenzene dyes to the quadruply hydrogen-bonding modules 2,7-diamido-1,8-naphthyridine (DAN) and 7-deazaguanine urea (DeUG) is described. The coupling of azobenzene dye 2 to mono-amido DAN units 4, 7, and 9 was effected by classic 4-(dimethylamino)pyridine (DMAP)-catalyzed peptide synthesis with N-(3-dimethylaminopropyl)-N'-ethyl carbodiimide hydrochloride (EDC) as activ...
متن کاملA highly stable quadruply hydrogen-bonded heterocomplex useful for supramolecular polymer blends.
The butyl urea of guanosine (UG) presents an ADDA hydrogen-bonding array that is complementary to the DAAD array of 2,7-diamido-1,8-naphthyridine (DAN). The stability of the DAN.UG complex was measured by fluorimetry using the fluorescence resonance energy transfer (FRET) from the naphthyridine ring to a coumarin 343 moiety linked covalently to the UG unit. The quadruply hydrogen-bonded complex...
متن کاملNanoscale technology of mucoadhesive interactions.
Nanoscale analysis may be used to design new types of mucoadhesive polymers. Understanding of the surface interactions between hydrophilic polymer surfaces and mucins can lead to improved adhesive bonding by hydrogen bonding. Alternatively, decoration of a mucoadhesive polymer surface with tethers of linear and block copolymers containing neutral or ionizable structures provides increased inter...
متن کاملHigh-affinity DNA base analogs as supramolecular, nanoscale promoters of macroscopic adhesion.
Adhesion phenomena are essential to many biological processes and to synthetic adhesives and manufactured coatings and composites. Supramolecular interactions are often implicated in various adhesion mechanisms. Recently, supramolecular building blocks, such as synthetic DNA base-pair mimics, have drawn attention in the context of molecular recognition, self-assembly, and supramolecular polymer...
متن کاملHydrogen bonding: Attractive arrays.
hydrogen bonding is considered by many to be the ‘master key’ of molecular recognition — owing to its relatively predictable strength and directionality — and plays a major role in the assembly of diverse non-covalent assemblies1. Consequently, the study and exploitation of hydrogen bonds has been central to the development of modern supramolecular chemistry. In particular, numerous applied set...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Organic letters
دوره 15 14 شماره
صفحات -
تاریخ انتشار 2013